System Interaction (Programming Perl)

25.4. System Interaction

Platforms that rely on a graphical user interface sometimes lack command lines, so programs requiring a command-line interface might not work everywhere. You can't do much about this, except upgrade.

Some other tips:

Some platforms can't delete or rename files that are in use, so remember to close files when you are done with them. Don't unlink or rename an open file. Don't tie or open a file already tied or opened; untie or close it first.
Don't open the same file more than once at a time for writing, since some operating systems put mandatory locks on such files.
Don't depend on a specific environment variable existing in %ENV, and don't assume that anything in %ENV will be case sensitive or case preserving. Don't assume Unix inheritance semantics for environment variables; on some systems, they may be visible to all other processes.
Don't use signals or %SIG.
Try to avoid filename globbing. Use opendir, readdir, and closedir instead. (As of release 5.6.0 of Perl, basic filename globbing is much more portable than it was, but some systems may still chafe under the Unixisms of the default interface if you try to get fancy.)
Don't assume specific values of the error numbers or strings stored in $!.